A groundbreaking new history of global health from one of the greatest leaders in the field. In Change Is Possible, public health legend William H. Foege and five coauthors chronicle the failures and successes of global health through the modern age, including the massive impacts of colonialism, religious groups, philanthropies, politics, NGOs, and more. Foege, who has served in local, national, and international public health contexts—including as the director of the Centers for Disease Control and Prevention—is uniquely qualified to reflect on the history of global health. He and his Rollins School of Public Health coauthors explain why colonialism has been the greatest disaster for global health, whereas military medicine may have been its greatest asset. From the rapid development of NGOs to the impact of pharmaceutical companies over the last 35 years to the hybrid programs that are now responsible for innovative contributions, the authors discuss multiple impacts on global health. In chapters with coauthors Paul Elish, Alison T. Hoover, Madison Gabriella Lee, Deborah Chen Tseng, and Kiera Chan, Foege explores additional essential topics such as the legacy of colonialism in global health, early philanthropy versus new philanthropy, and how to promote positive change. Foege also shares critical lessons from the smallpox campaign—a disease he helped eradicate—and how these historical lessons can be applied in global health work today. The book's research and reflections make this an essential book for students and readers interested in global health. In a narrative that is both deeply personal and universal, Foege shares lessons learned and personal experiences that craft a strikingly new history of global health.