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CHAPTER I: INTRODUCTION: Epilepsy signs and symptoms, seizers and its types and causes of epilepsy CHAPTER II: REVIEW OF LITERATURE: Epidemiology of Epilepsy, Etiology of Epilepsy, Mortality, Classification of Epileptic Seizures, Pilocarpine, Role of Neurotransmitters in Epilepsy: Epinephrine and Norepinephrine, Dopamine, GABA, Acetylcholine, Serotonin synthesis and metabolism, Anatomy of Serotonin System, Serotonin Receptors, Classification of Serotonin receptors: 5-HT1 Receptor, 5-HT2 Receptor, 5-HT3 Receptor, 5-HT4 Receptor, 5-HT5 Receptor, 5-HT6 Receptor, 5-HT7 Receptor, 5-HT2C Receptor Structure, Functional Effects Mediated via the 5-HT2C Receptor Signal Transduction, Serotonin and Serotonin Receptors in Epilepsy, 5-HT2C Receptors and Epilepsy, Glutamate, Glutamate and Glutamate Receptors in Epilepsy, Ionotropic Receptors - NMDA Receptors, Functional Effects Mediated Via the NMDA Receptor Signal Transduction, NMDA receptors and Epilepsy, Metabotropic Glutamate Receptors, Glutamate Transporter, Signal transduction through Second Messengers Inositol 1, 4, 5-trisphosphate (IP3), Cyclic Guanosine Monophosphate (cGMP), Cyclic Adenosine Monophosphate (cAMP), Pathophysiology of Tempo