Bioinformatics and Computational Biology is a compendium of articles and papers that were presented at BIOCOMP '14, an international conference that serves researchers, scholars, professionals, students, and academicians. Selected Topics include: * Gene Expression and Representation, Microarray, Sequencing, Alignment, and Related Bioinformatics Issues * Computational Biology and Medical Applications + Health Informatics and Related Issues * Protein Classification and Structure Prediction, Folding, and Computational Structural Biology + Drug Design * Machine Learning, Data and Information Mining + Signal Processing and Data Quality Enhancement + Databases * Posters * Late Breaking Papers and Position Papers: Bioinformatics and Computational Biology