This book includes peer reviewed articles from the Fifth International Conference on Intelligent Systems and Networks (ICISN 2025), held at Hanoi in Vietnam. It presents latest research outcomes and results of cutting-edge work reported by the authors, which are very useful for the researchers and industry practitioners. The scope of the proceedings include, but not limited to Foundations of Computer Science; Computational Intelligence, Language and Speech Processing; Software Engineering and Software Development Methods; Wireless Communications, Signal Processing for Communications, Next-Generation Mobile Networks, Internet-of-Things and Sensor Systems; etc. We believe that selected manuscripts will be of great value as references for these emerging areas of research.