This book constitutes the proceedings of the 10th International Conference on Business Process Management, BPM 2012, held in Tallinn, Estonia, in September 2012. The 17 regular papers and 7 short papers included in this volume were carefully reviewed and selected from 126 submissions. The book also features two keynote lectures which were given at the conference. The papers are organized in topical sections named: process quality; conformance and compliance; BPM applications; process model analysis; BPM and the cloud; requirements and performance; process mining; and refactoring and optimization.