This two-volume set CCIS 2432-2433 constitutes the refereed proceedings of the 10th China Health Information Processing Conference, CHIP 2024, held in Fuzhou, China, during November 15–17, 2024. The 32 full papers included in this set were carefully reviewed and selected from 65 submissions. They are organized in topical sections as follows: biomedical data processing and model application; mental health and disease prediction; and drug prediction and knowledge map.