What learning, teaching, and education will be in the next future is an open question. Nevertheless, believing that an increasing prevalence of AI may not influence the education field seems objectively unlikely. In recent years, the new renaissance of AI has stimulated discussion on how advances in AI can influence the educational sector and the future educational policies and the impact of AI on Technology-Enhanced Learning (TEL). On the other side, the attention of the education sector in artificial intelligence is complemented by the consideration that, since the early days of AI, researchers have shown for the education sector, which has often seen education as one of the preferred application areas. The interaction between the AI and TEL research fields led to the investigation of how the advance in AI could support the development of flexible, inclusive, personalized, engaging, and effective learning tools. Besides, research in this area could be a powerful tool to open the "learning black box" by providing a deeper understanding of how learning occurs. The proposed Research Topic aims to gather contributions that provide a comprehensive picture of how AI is changing educational practices and how the key stakeholders in the educational community (i.e., students, teachers, faculty, and families) perceive this ongoing change. Relevant topics include (but are not limited to): AI applications in real-world educational settings Intelligent Tutoring Systems Adaptive learning environments Learning design and AI Students profiling: definition of the student model and ethical implications Intelligent techniques for objective and integrated students evaluation in TEL Teachers' competencies for effective integration of AI into Education Teachers’ perceptions of AI: prejudices and attitudes The role of cognitive architectures in