This book constitutes the refereed conference proceedings of the 11th International Conference on Mobile Wireless Middleware, Operating Systems and Applications, MOBILWARE 2022, via Virtual Event on 28-29, 2022 Due to COVID-19 pandemic the conference was held virtually. The 23 revised full papers were reviewed and selected from 59 submissions and are organized in tracks on Middleware, Wireless, and Future Networks; Integrated Satellite-Terrestrial Information Network; and Integrated Satellite-Terrestrial Intelligent Information Processing, Decision and Planning.