A Life Course Approach to the Epidemiology of Chronic Diseases and Ageing, Third Edition outlines how biological and social factors during gestation, childhood, adolescence and earlier adult life influence later life health and disease. It also looks at whether and how to intervene to improve health outcomes. This revised third edition is fully updated to reflect the new data that has emerged as well as our new understanding of health and global challenges. It brings new chapters on a life course approach to the long-term health consequences of climate change and the COVID-19 pandemic. It examines the current and potential use of new technologies, methods and collaborative approaches in life course studies and provides updated reviews of the latest life course evidence for age-related chronic diseases. It discusses how life course research is being used, and could be used, to improve population health in high, middle, and low-income countries, identifying how and when interventions may be most effective. New chapters on multimorbidity, translational geroscience and exposomics have also been added.