The two-volume set LNCS 7565 and 7566 constitutes the refereed proceedings of three confederated international conferences: Cooperative Information Systems (CoopIS 2012), Distributed Objects and Applications - Secure Virtual Infrastructures (DOA-SVI 2012), and Ontologies, DataBases and Applications of SEmantics (ODBASE 2012) held as part of OTM 2012 in September 2012 in Rome, Italy. The 53 revised full papers presented were carefully reviewed and selected from a total of 169 submissions. The 22 full papers included in the first volume constitute the proceedings of CoopIS 2012 and are organized in topical sections on business process design; process verification and analysis; service-oriented architectures and cloud; security, risk, and prediction; discovery and detection; collaboration; and 5 short papers.