The Zurich polymath Conrad Gessner (1516-1565) is known as the founder of zoology and plant geography, the father of bibliography, editor of ancient texts, and author of one of the most important paleontological works of the sixteenth century. While preparing his extensive work on plants, he died unexpectedly and early from the plague. Gessner's interest in the natural sciences was rooted, on the one hand, in the new conception of nature that emerged with the Renaissance, and, on the other hand, in the creation theology of the Reformation, which considered nature as a second book of God's revelation next to the Bible. This richly illustrated and erudite biography is the first biography of Gessner to appear in English. This biography is a translation of Conrad Gessner (1516-1565): Universalgelehrter und Naturforscher der Renaissance (Basel: NZZ Libro, 2016).