Thanksgiving 2010. The world prepares for the first lunar eclipse to take place on the winter solstice since the year 1638. Crop circles, strange animals, disappearances, and UFOs permeate the empty countryside of the American South. Odette "Odie" Tucker is a first-generation college student, returning home from Boston to rural Arkansas for the holidays. On the drive home, she endures a pill-induced abortion in a gas station bathroom, the product of a recent rape she has told no one about. On a whim, she 'rescues' the clump of expelled cells in a plastic water bottle. At home, Odie faces the suppressed feelings of abandonment from her family and lifelong best friend Dale, an out butch lesbian Odie is too afraid to admit she's in love with. When Odie's abortion becomes sentient and possesses her, she begins to live vicariously through its complete embrace of life, love, sex, violence, and vengeance.