Particle Beam Therapy: contemporary trends and reviews addresses the importance of charged particle beam therapy. Charged particles with their favorable depth of dose distribution are ideal for treating tumors located inside the body.With all the potential advancements from physics and radiobiology, the field of charged particle beam therapy is still facing many challenges and is far from reaching its full capacity and application, especially how to improve patients’ survival and 40 quality of life as well as to be cost effective.