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Excerpt from The Principles of Pathology, Vol. 2: Systemic Pathology Little in the Way of preface is here needed by those who have made themselves familiar with the first volume of this work. In that we dealt with the causes of disease and the morbid and reactive processes; now we pass forward to discuss the results of disease as it affects the different systems and, through them, the body as a whole. We will not pretend that our first volume was other than bulky; to many readers it may have seemed that the treatment of the various sections was unnecessarily full. These same readers may be inclined to consider that, working upon the same scale, the subject matter of special pathology demands at least twice the space now afforded, or, put otherwise, that our treatment of systemic pathology is as condensed as that of general pathology was diffuse. A little consideration will, we trust, show that our method, if unusual, is, nevertheless, rational. Pro vided that the student has acquired a good grasp of the principles of general pathology, he has but to apply those principles in order to become possessed of a sound basis of special pathology. If, to cite examples, he be well acquainted with the modifications of the inammatory process as it affects parenchymatous and connective tissues, epithelial and serous membranes, respectively; with the different forms of tumors originating from the different orders of cells; with the particular orders of degeneration likely to affect cells of one type or another; then his familiarity with the histology of the different organs gives him the key to special pathological histology. Taking this knowledge for granted, it becomes unnecessary to describe in detail the different conditions of inammation, tumor growth, and degeneration that affect the different organs. Where these conditions are typical in their manifestations their existence alone need be cited. It is only when their manifestations present peculiarities that extended