Author Description

1115121BasicsforBioinfbrmatics.XuegongZhangXueyaZhouandXiaowoWang1.1WhatIsl3ioinformatics1.2SomeBasicBiology1.2.1ScaleandTime.1.2.2Cells.1.2.3DNAandChromosome1.2.4TheCen~a1Dogma.1.2.5GenesandtheGenome.1.2.6MeasurementsAlongtheCentralDogma1.2.7DNASequencing1.2.8TranscriptomicsandDNAMicroarrays1.2.9ProteomicsandMassSpectrometry.1.2.10ChIP-ChipandChIP.Seq1.3ExampleTopicsofBioinformatics1.3.1ExamplesofAlgorithmaticTopics1.3.2ExamplesofStatisticalTopics.1.3.3MachineLearningandPatternRecognitionExamples1.3.4BasicPrinciplesofGenetics.References2BasicStatisticsforBioinformatics.YuanlieLinandRuiJiang2.1Introduction.2.2FoundationsofStatistics2.2.1Probabilities2.2.2RandomVariables2.2.3MultipleRandomVariables2.2.4Distributions.2.2.5randomsampling.2.2.6suf.cientstatistics2.3pointestimation2.3.1methodofmoments.2.3.2maximumlikelihoodestimators2.3.3bayesestimators2.3.4meansquarederror.2.4hypothesistesting2.4.1likelihoodratiotests2.4.2errorprobabilitiesandthepowerfunction2.4.3p-values2.4.4somewidelyusedtests2.5intervalestimation2.