Author Description

This volume is the only current, comprehensive book on the nerve growth cone, the dynamic cell structure that plays a key role in establishing the specific neuronal interconnections that determine neural circuitry, and thus, behavior. Written by more than 30 leading investigators, the book describes all aspects of contemporary research on nerve growth cones, from their individual molecular components to their behavior within intact living animals. The contributors review the most recent in vitro and in vivo studies using the most advanced techniques of biochemistry, molecular and cell biology, and microscopy, including, computerized video technology. The 33 chapters are organized in four sections: intrinsic mechanisms of growth cone motility, extrinsic factors that regulate growth cone migration, growth cone behavior within intact developing tissues, and growth cones during regeneration. Each section begins with an introductory overview of the important issues and current knowledge in the area. More than 150 illustrations complement the text.