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Fish and other aquatic biota may be harmed by pesticide-contaminated water.Pesticide surface runoff into rivers and streams can be highly lethal to aquatic life, sometimes killing all the fish in a particular stream.Application of herbicides to bodies of water can cause fish kills when the dead plants rot and use up the water's oxygen, suffocating the fish.Some herbicides, such as copper sulfite, that are applied to water to kill plants are toxic to fish and other water animals at concentrations similar to those used to kill the plants. 35] Repeated exposure to sublethal doses of some pesticides can cause physiological and behavioral changes in fish that reduce populations, such as abandonment of nests and broods, decreased immunity to disease, and increased failure to avoid predators.