Artificial Intelligence and Multimodal Signal Processing in Human-Machine Interaction presents an overview of an emerging field that is concerned with exploiting multiple modalities of communication in both Artificial Intelligence and Human-Machine Interaction. The book not only provides cross disciplinary research in the fields of multimodal signal acquisition and sensing, analysis, IoTs (Internet of Things), Artificial Intelligence, and system architectures, it also evaluates the role of Artificial Intelligence I in relation to the realization of contemporary Human Machine Interaction (HMI) systems. Readers are introduced to the multimodal signals and their role in the identification of the intended subjects, mental state and the realization of HMI systems are explored, and the applications of signal processing and machine/ensemble/deep learning for HMIs are assessed. A description of proposed methodologies is provided, and related works are also presented. This is a valuable resource for researchers, health professionals, postgraduate students, post doc researchers and faculty members in the fields of HMIs, Brain-Computer Interface (BCI), Prosthesis, Computer vision, and Mental state estimation, and all those who wish to broaden their knowledge in the allied field.