The focus of this edited volume is twofold: to better understand current regional transformations; and to discuss what new developments mean for how we theorize non-European regionalism and regionalist governance. The book provides an original and grounded analysis of post-hegemonic and post-trade arrangements in the areas of finance, security, development and civil society. By observing these points the authors hope to open a new space for an analysis of the transformative capacity and the political resilience of new regional spaces and institutional arrangements. Theoretically, by focusing on the question of post-trade regional governance we hope to challenge New Regionalist approaches that have usefully embraced issues beyond mainstream EU studies (in particular the links between the regional, the international and the local), yet had assumed regionalism as taking place within and modelled by neoliberal economics. The approach taken here supersedes the old categorizations of 'old' and 'new' regionalism to explain new realities that are not taking place within and modelled by neoliberal economics. The chapters will contribute to the analytical field of (comparative) regionalism by addressing new questions about how transformative post-hegemonic regionalism(s) are in terms of regional space and new polities. Finally, the collection is an open invitation to engage EU and other studies on regionalism as Latin America matters for the knowledge it can provide on pressing questions such as flexibility, the use of informal politics and power, and the continuing widening-versus-deepening debate understanding regionalism and regionalization for other regions of the world.