This book constitutes the proceedings of the Second International Workshop, AI4Research 2025, and First International Workshop, SEAS 2025, which were held in conjunction with AAAI 2025, Philadelphia, PA, USA, during February 25–March 4, 2025. AI4Research 2025 presented 8 full papers from 35 submissions. The papers covered diverse areas such as agent debate evaluation, taxonomy expansion, hypothesis generation, AI4Research benchmarks, caption generation, drug discovery, and financial auditing. SEAS 2025 accepted 7 full papers from 17 submissions. These papers explore the efficiency and scalability of AI models.