This book constitutes the proceedings of the 15th International Conference on Risks and Security of Internet and Systems, CRiTIS 2020, which took place during November 4-6, 2020. The conference was originally planned to take place in Paris, France, but had to change to an online format due to the COVID-19 pandemic. The 16 full and 7 short papers included in this volume were carefully reviewed and selected from 44 submissions. In addition, the book contains one invited talk in full paper length. The papers were organized in topical sections named: vulnerabilities, attacks and intrusion detection; TLS, openness and security control; access control, risk assessment and security knowledge; risk analysis, neural networks and Web protection; infrastructure security and malware detection.