The purpose of health technology assessment (HTA) is to provide health care decision-makers with evidence to make informed decisions concerning the introduction, allocation, & cost-effective use of medical technologies. This guide is a directory that focusses on Internet sites related to HTA, particularly those that may be useful for those involved in health care in Alberta. It is arranged in the following categories: bibliographic databases; Canadian & international HTA sites; clinical trials; complementary & alternative medicine; evidence-based medicine & critical appraisal; government & research information; health economics; practice guidelines; quality of life; and sources of further information.