This book intends to report the peripheral effects of corticotropin-releasing factor (hormone) family (CRFs), different from its role in the CRH-ACTH-adrenocorticoids axis. The book collects data about CRFs’ peripheral secretion from many types of cells and their effects on cardiovascular functions and carcinogenesis. The book is likely to be of interest to graduate students and researchers in the field of biomedicine, especially in the field of cardiovascular diseases and cancer.