This book constitutes the refereed proceedings of the 19th International Conference on Mobile Web and Intelligent Information Systems, MobiWIS 2023, held in Marrakech, Morocco, during August 14–16, 2023. The 18 full papers and 1 short papers presented in this book were carefully reviewed and selected from 54 submissions. The papers are divided into the following topical sections: smart and intelligent systems; digital systems in healthcare services; SDN, IoT and edge computing; mobile interfaces and interactivity; machine learning and stochastic methods; and advanced mobile applications.