This book constitutes the thoroughly refereed proceedings of the 10th International Conference on Intelligent Human Computer Interaction, IHCI 2018, held in Allahabad, India, in December 2018. The 28 regular papers presented were carefully reviewed and selected from 89 submissions. The papers have been organized in the following topical sections: ECG, EEG -based and Other Multimodal Interactions; Natural Language, Speech and Dialogue Processing; Modeling Human Cognitive Processes and Simulation; Image and Vision Based Interactions; and Applications of HCI.