This book presents the proceedings of the KES International Conferences on Innovation in Medicine and Healthcare (KES-InMed-22), held in Rhodes, Greece, on June 20-22, 2022. Covering a number of key areas, including digital IT architecture in health care; advanced ICT for medicine and health care; biomedical engineering, trends, research, and technologies; and healthcare support systems, this book is a valuable resource for researchers, managers, industrialists, and anyone wishing to gain an overview of the latest research in these fields.