Author Description

Accessible and user-friendly, Cell Biology, 4th Edition, provides a strong foundation for students entering health care career paths as well as higher level research areas. Clear, readable text and high-quality, detailed illustrations help readers quickly grasp challenging content—all focusing on cellular processes without delving into molecular processes. Drs. Thomas D. Pollard, William C. Earnshaw, Jennifer Lippincott-Schwartz, and author/illustrator Dr. Graham Johnson have thoroughly updated this popular text to ensure its relevance for students in biology, biotechnology, medicine, and pathophysiology, covering key principles of cellular function and explaining how molecular defects lead to cellular dysfunction and cause human disease. Balances depth of detail with clear, readable explanations, providing a concise but comprehensive overview of this complex topic. An intuitive chapter flow leads with genome organization, gene expression, and RNA processing as a foundation for understanding cellular interactions and cell physiology. Brings cellular biology to life for students in clinically focused programs, as breakthroughs in areas like gene editing, epigenetics, and the understanding of the microbiome continue to grow in clinical application. Features unique illustrations with realistic proportions and relationships, including many new instructive illustrations— from structure of volume-regulated LRRC8 Cl -1 channel and generation of circular RNAs from introns … to deadenylation cycles and assembly of SARS CoV-2). Covers new topics such as optogenetics and super resolution fluorescence microscopy; predicting 3D protein structure; gene expression profiling by single-cell RNA sequencing; protein misfolding and human disease; mechanism of CFTR and new drugs to treat cystic fibrosis; new insights on carriers and channels and their clinical implications; mitochondrial genomes