When newly initiated Defenders Valerie, Gabe, and John are called to rescue victims from the haunted Buford Hospital, they arrive to find there is more to fear than ghosts within the endless, dark, tiled hallways. Even the two people they've come to rescue are not to be trusted. Despite being incorporeal, the ghosts at Buford Hospital are deadly and can somehow wield real weapons with the intent to keep the Defenders there for all eternity. And the evil that holds the spirits captive is something Valerie, Gabe, and John have never before encountered. As Defenders, they are charged with protecting the world from evil, but that might not be so easy when they are strapped to an embalming table?