This book constitutes extended, revised, and selected papers from the 10th International Symposium of Artificial Intelligence supported by the Japanese Society for Artificial Intelligence, JSAI-isAI 2018. It was held in November 2018 in Yokohama, Japan. The 28 paper full papers and 5 short papers were carefully selected from 97 submissions. The papers selected cover topics in Artificial Intelligence, such as AI and law, business intelligence, human intelligence, logic and engineering, and data analytics and applications.