Izzy's own beloved pets are dressed to the nines for the grand opening of Trendy Tails. Feisty feline Jinx is large and in charge, and happy mutt Packer is lapping up the attention. Izzy and her best friend Rena have their hands full meeting Merryville's menagerie and serving tasty pupcakes and kitty canapes from their "barkery." The last thing they need is the town's local activist, Sherry Harper, scaring off customers and getting tongues wagging by picketing the event. The two manage to stop Sherry's protest in its tracks, but the trouble for Trendy Tails is just beginning. Sherry is found murdered in back of the shop, and Rena is immediately named as the lead suspect. Now Izzy and her furry friends have a new pet project, collaring a killer.