Here is a unique, practical volume that covers the full range of issues surrounding the expanding field of nucleic acid sequencing. It provides advice on the methods of Sanger, Maxam, and Gilbert, while paying close attention to such recent technological advances as the development ofautomated sequencing and the refinement of computer hardware and software. This unique interdisciplinary guide also includes information on how the new methodologies have affected RNA sequencing, and other areas as diverse as archaeology and forensic work. into RNA sequencing, and other areas asdiverse as archaeology and forensic work.