Author Description

This substance was assessed for potential effects of indirect exposure in the general environment on human health as well as environmental effects. Occupational exposure was not addressed.<br> <br> N N-Dimethylformamide is an organic solvent produced in large quantities throughout the world. It is used in the chemical industry as a solvent, an intermediate, and an additive. DMF is readily absorbed following oral, dermal, or inhalation exposure. The liver is the target organ for the toxicity of DMF in humans. There is no convincing, consistent evidence of increase in tumours at any site associated with exposure to DMF in the occupational environment. There is also little convincing evidence of genotoxicity in populations occupationally exposed to DMF.