Treatment-resistant Major Depression And Bipolar Disorder Are Highly Prevalent And Disabling Conditions Associated With Substantial Morbidity And Mortality. The Assessment And Management Of Refractory Patients With Mood Disorders Is A Major Clinical Challenge For Mental Health Providers. Part Of The Oxford Psychiatry Library (opl) Series, This Pocketbook Provides A Concise View Of The Current Definitions, Assessment And Evidence-based Management Of Treatment-resistant Mood Disorders And Reviews Novel Therapeutic Targets For Mood Disorders, Which May Enhance The Therapeutic Armamentarium Of Clinicians In The Near Future. The Pocketbook Serves As A Useful Guide For Mental Health Practitioners, Including Psychiatrists, Clinical Psychologists, Trainees, And Interested Primary Care Physicians.