This book constitutes the refereed proceedings of the 6th International Conference on the Theory and Application of Cryptographic Techniques in Africa, AFRICACRYPT 2013, held in Cairo, Egypt, in June 2013. The 26 papers presented were carefully reviewed and selected from 77 submissions. They cover the following topics: secret-key and public-key cryptography and cryptanalysis, efficient implementation, cryptographic protocols, design of cryptographic schemes, security proofs, foundations and complexity theory, information theory, multi-party computation, elliptic curves, and lattices.