Author Description

The medicinal value of different species of S. lappa has been known for long time. No information about its antipyretic potential has been observed in the literature reviewed. Hence the present study was designed to evaluate the anti- pyretic potential of S. lappa roots.For this purpose, roots of S. lappa were sequentially extracted with five different solvents (viz. petroleum ether, chloroform, acetone, methanol and water) in order of their increasing polarity using a soxhlet extractor. All the extracts were qualitatively analyzed for their phytoconstituents. Further the antipyretic potential of all the extracts was evaluated using Brewer s yeast induced pyrexia in Albino rats of Wistar strain. The results were tested for their significance by using one way ANOVA analysis by comparing with that of the control group at corresponding hours. Out of various extracts Petroleum ether extract of roots of S. lappa has shown significant reduction in body temperature as compared with control group and its effect is comparable to the standard drug paracetamol. Finally it could be concluded that roots of S. lappa possess good antipyretic potential.