This book presents 48 selected papers focused on Health Care Applications from the 23rd International Conference on Hybrid Intelligent Systems, which was held in five different cities namely Olten, Switzerland; Porto, Portugal; Kaunas, Lithuania; Greater Noida, India; Kochi, India and in online mode. The 23rd International Conference on Hybrid Intelligent Systems (HIS 2023) was focusing on synergistic combinations of multiple approaches to develop the next generation of intelligent systems. HIS 2023 had contributions by authors from 44 countries. This book offers a valuable reference guide for all medical doctors, scientists, academicians, researchers, students, and practitioners in the field of artificial intelligence and smart health care.