In recent years, a number of new developments have greatly enhanced our understanding of the aetiology, pathogenesis, and management of osteoarthritis. Understanding of the mechanism of cartilege breakdown has advanced, and new evidence from animal models have shown that the development and progression of osteoarthritis can be prevented or retarded pharmacologically. With more and more cases of this disease being seen each year, there are extensive research programs underway to find effective treatments for this disease. Osteoarthrities brings together an international team of acclaimed experts on this prevalent disease to provide a comprehensive textbook examining all aspects of this increasingly common condition. Included amongst others, are sections describing the pathogenesis of osteoarthritis, its clinical features, and the standard approaches to diagnosis. There are also sections covering in depth, the management of OA, and the prospects for pharmacological treatments of joint breakdown in ostoarthritis. While being an important text for rheumatologists and orthopedic surgeons, it will also be of great interest to physical therapists, radiologists, pathologists, epidemiologists, and general practitioners. Extensive illustrated, and incorporating the most recent advances in OA research, Osteoarthritis is the definitive work in this highly important disease.