This book covers many aspects of innovation theory, evolutionary economics, economic geography, and simulation models. It is one of the first books to comprehensively and systematically focus on the evolution of regional innovation based on provincial experience in emerging economics, including stylized facts, theoretical explanation, and simulation. The book is devoted to a pioneering process-based regional innovation matrix used for classifying a regional innovation model, which is illustrated by real-world cases and data analyses. The topics addressed here include path dependency, lock-in, routines, variations, selectivity, regional gap, innovation progress, agglomeration, and innovation efficiency. The simulation methods describing the dynamics of regional innovation evaluation on economics are developed as well. The primary objective of this work is to provide a tractable and useful regional governance tool for researchers and policy makers in regional science, human geography, and related disciplines. The book is highly recommended to readers who seek more insight into the continuous development of China or regional development gaps.