This book gathers research contributions on recent advances in intelligent and distributed computing. A major focus is placed on new techniques and applications for several highlydemanded research directions: Internet of Things, Cloud Computing and Big Data, Data Mining and Machine Learning, Multi-agent and Service-Based Distributed Systems, Distributed Algorithms and Optimization, Modeling Operational Processes, Social Network Analysis and Inappropriate Content Counteraction, Cyber-Physical Security and Safety, Intelligent Distributed Decision Support Systems, Intelligent Human-Machine Interfaces, VisualAnalytics and others. The book represents the peer-reviewed proceedings of the 13thInternational Symposium on Intelligent Distributed Computing (IDC 2019), which was held in St. Petersburg, Russia, from October 7 to 9, 2019.