This book is the first work to conduct the emergency logistics optimization problem under the epidemic environment (whether natural or man-made), which provides a new perspective for the application of optimization theory. In this book, the research methods involve epidemic dynamics, scenario-based emergency decision-making method, big data which combines the traditional and emerging technologies. The authors take epidemic outbreak as the research object and deeply integrate the epidemic spread model with the optimization model of emergency resource scheduling, which opens up a novel application area of operations research.