Synthesizing knowledge from both basic and clinical disciplines, this book critically reviews our current understanding of schizophrenia in terms of its biochemistry and pharmacological treatment. The book examines different hypotheses of drug action and evaluates the efficacy of various treatments. Contributors discuss the choice of diagnostic system; examine the impact of social factors; and describe statistical, epidemiological, and treatment studies. The volume provides a thorough review of biological and psychological treatments-- conventional and experimental-- based on systematic controlled studies.